Do Hypogonadal Older Men Benefit from Testosterone Therapy?

Introduction
For younger males with profound hypogonadism, such as those with hypogonadotropic hypogonadism due to Kallmann’s syndrome, testosterone is routinely prescribed to induce and maintain secondary sex characteristics, to allow for normal sexual function, to promote a male body composition, and to provide estrogen for bone health. The situation is more complex when it comes to older men with borderline low testosterone levels and nonspecific symptoms of hypogonadism. The Endocrine Society recently published a Clinical Practice Guideline entitled “Testosterone Therapy in Ad...