Management of Rising Prostate-Specific Antigen after Treatment for Localized Prostate Cancer

CASE PRESENTATION
A 60-year-old man had a screening prostate-specific antigen that was 7.0 ng/mL. The digital rectal exam was normal. A transrectal ultrasound and prostate biopsy revealed moderately well differentiated adenocarcinoma of the prostate, with a Gleason score of 7 (3 + 4). The bone scan and computed tomography (CT) scan of the abdomen and pelvis were negative for metastatic disease. The patient had a radical retropubic prostatectomy. The regional lymph nodes were negative, and the surgical margins were clear of prostate cancer, T1c disease. The postoperative PSA was undete...